Neurohypophyseal Peptides and Psychopathology

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Threshold and Receptor Reserve in the Action of Neurohypophyseal Peptides

The interrelationship of several physiological receptors which influence the hydroosmotic response of the toad urinary bladder was studied employing neurohypophyseal peptides, prostaglandin E(1), theophylline, and cyclic nucleotides. The binding property of agonists (pD(2)), synergists (pS(2)), competitive antagonists (pA(2)), and noncompetitive antagonists (pD(2)') was determined after a suita...

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A Sensitive Hydroosmotic Toad Bladder Assay A nity and intrinsic activity of neurohypophyseal peptides

I N T R O D U C T I O N T h e m a m m a l i a n ant id iure t ic ho rmone , vasopressin, modif ies the p e r m e a b i l i t y to wa t e r of the distal n e p h r o n and t he r eby accelera tes osmotic equ i l ib ra t ion of the fo rming ur ine wi th the renal interst i t ial fluid (4). Similar ly , neu ro hypophysea l pept ides increase the ra te of wa t e r m o v e m e n t a long an osmot ic...

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ژورنال

عنوان ژورنال: Hormone Research

سال: 1992

ISSN: 1423-0046,0301-0163

DOI: 10.1159/000182396